Material Safety Data Sheet
L-Adrenaline Hydrochloride Solution (1:10,000)

ACC# 45370
Section 1 - Chemical Product and Company Identification

MSDS Name: L-Adrenaline Hydrochloride Solution (1:10,000)
Catalog Numbers: S701862
Synonyms:
L-Epinephrine Hydrochloride; L-3,4-Dihydroxy-.alpha.-((methylamino)methyl)benzyl alcohol Hydrochloride
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
7732-18-5Water 99.99 231-791-2
unlisted
51-43-4L-Adrenaline balance 200-098-7

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear, colorless liquid.
Caution! May cause irritation. May cause fetal effects based upon animal studies. This is expected to be a low hazard for usual industrial handling.
Target Organs: None.


Potential Health Effects
Eye: May cause eye irritation. Low hazard for normal industrial handling.
Skin: May cause skin irritation. Low hazard for usual industrial handling.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Expected to be a low ingestion hazard.
Inhalation: May cause respiratory tract irritation. Low hazard for usual industrial handling.
Chronic: No information found.

Section 4 - First Aid Measures


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use extinguishing media most appropriate for the surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Use with adequate ventilation.
Storage: Store in a cool, dry place. Keep containers tightly closed.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Water none listed none listed none listed
0.1 mg/m3 TWA (listed under Tellurium). 0.1 mg/m3 TWA (listed under Tellurium).25 mg/m3 IDLH (listed under Tellurium). 0.1 mg/m3 TWA (listed under Tellurium).
L-Adrenaline none listed none listed none listed

OSHA Vacated PELs: Water: No OSHA Vacated PELs are listed for this chemical. : No OSHA Vacated PELs are listed for this chemical. L-Adrenaline: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear, colorless
Odor: odorless
pH: Not available.
Vapor Pressure: 14 mm Hg
Vapor Density: 0.7
Evaporation Rate:>1
Viscosity: Not available.
Boiling Point: 100 deg C
Freezing/Melting Point:0 deg C
Decomposition Temperature:Not available.
Solubility: Soluble in water.
Specific Gravity/Density:1.0
Molecular Formula:C9H11NO3
Molecular Weight:181.0819

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: None reported.
Incompatibilities with Other Materials: None reported.
Hazardous Decomposition Products: None.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 7732-18-5: ZC0110000      
CAS# unlisted.      
CAS# 51-43-4: DO2625000
LD50/LC50:
CAS# 7732-18-5:
     Oral, rat: LD50 = >90 mL/kg;
CAS# :
CAS# 51-43-4:
     Skin, rat: LD50 = 62 mg/kg;
Carcinogenicity:
CAS# 7732-18-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# : Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 51-43-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No data available.
Teratogenicity: L-Adrenaline HCl is an experimental teratogen.
Reproductive Effects: L-Adrenaline HCl has caused fetal effects in experiments with laboratory animals.
Mutagenicity: No data available.
Neurotoxicity: No data available.
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: CAS# 51-43-4: waste number P042.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: Not regulated as a hazardous material No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 7732-18-5 is listed on the TSCA inventory.
     CAS# is not listed on the TSCA inventory.      It is for research and development use only.
     CAS# 51-43-4 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     CAS# 51-43-4: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 51-43-4: acute, chronic.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
     CAS# can be found on the following state right to know lists: California, (listed as Tellurium), New Jersey, (listed as Tellurium), Pennsylvania, (listed as Tellurium), Minnesota, (listed as Tellurium), Massachusetts, (listed as Tellurium).
     CAS# 51-43-4 can be found on the following state right to know lists: New Jersey, Pennsylvania, Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
      Not available.
Risk Phrases:


Safety Phrases:


WGK (Water Danger/Protection)

     CAS# 7732-18-5: No information available.
     CAS# : No information available.
     CAS# 51-43-4: 3
Canada - DSL/NDSL
     CAS# 7732-18-5 is listed on Canada's DSL List.
     CAS# 51-43-4 is listed on Canada's DSL List.
Canada - WHMIS
     WHMIS: Not available.
Canadian Ingredient Disclosure List
     CAS# (listed as Tellurium) is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 9/02/1997
Revision #3 Date: 7/29/2002

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.